Penicillin-binding protein 2 inactivation in Escherichia coli results in cell division inhibition, which is relieved by FtsZ overexpression.

Aminoacyl-tRNA synthetase mutants of Escherichia coli are resistant to amdinocillin (mecillinam), a beta-lactam antibiotic which specifically binds penicillin-binding protein 2 (PBP2) and prevents cell wall elongation with concomitant cell death. The leuS(Ts) strain, in which leucyl-tRNA synthetase...

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Publié dans:	J Bacteriol
Auteurs principaux:	Vinella, D, Joseleau-Petit, D, Thévenet, D, Bouloc, P, D'Ari, R
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206783/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8407846/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.20.6704-6710.1993
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