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The pSC101 par locus alters protein-DNA interactions in vivo at the plasmid replication origin.

We report here direct evidence that mutations in the par locus affect protein-DNA interactions in vivo at the replication origin of plasmid pSC101. Concomitant with par-mediated plasmid stabilization, two sites in the origin region show an altered methylation pattern as detected by in vivo footprint...

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Udgivet i:J Bacteriol
Principais autores: Ingmer, H, Cohen, S N
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206688/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8376350/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.18.6046-6048.1993
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