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Self-Assembly and DNA Binding of the Blocking Factor in X Chromosome Inactivation

X chromosome inactivation (XCI) is the phenomenon occurring in female mammals whereby dosage compensation of X-linked genes is obtained by transcriptional silencing of one of their two X chromosomes, randomly chosen during early embryo development. The earliest steps of random X-inactivation, involv...

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Détails bibliographiques
Auteurs principaux: Nicodemi, Mario, Prisco, Antonella
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2065890/
https://ncbi.nlm.nih.gov/pubmed/17997592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.0030210
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