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Cloning and characterization of a gene whose product is a trans-activator of anthrax toxin synthesis.

The 184-kb Bacillus anthracis plasmid pXO1, which is required for virulence, contains three genes encoding the protein components of anthrax toxin, cya (edema factor gene), lef (lethal factor gene), and pag (protective antigen gene). Expression of the three proteins is induced by bicarbonate or seru...

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Détails bibliographiques
Publié dans:J Bacteriol
Auteurs principaux: Uchida, I, Hornung, J M, Thorne, C B, Klimpel, K R, Leppla, S H
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1993
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206586/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8366021/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.175.17.5329-5338.1993
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