Lack of evidence of WNT3A as a candidate gene for congenital vertebral malformations

BACKGROUND: Prior investigations have not identified a major locus for vertebral malformations, providing evidence that there is genetic heterogeneity for this condition. WNT3A has recently been identified as a negative regulator of Notch signaling and somitogenesis. Mice with mutations in Wnt3a dev...

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Detalhes bibliográficos
Main Authors: Ghebranious, Nader, Raggio, Cathleen L, Blank, Robert D, McPherson, Elizabeth, Burmester, James K, Ivacic, Lynn, Rasmussen, Kristen, Kislow, Jennifer, Glurich, Ingrid, Jacobsen, F Stig, Faciszewski, Thomas, Pauli, Richard M, Boachie-Adjei, Oheneba, Giampietro, Philip F
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central|1 2007
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064903/
https://ncbi.nlm.nih.gov/pubmed/17888180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1748-7161-2-13
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