Hif-1α regulates differentiation of limb bud mesenchyme and joint development

Recent evidence suggests that low oxygen tension (hypoxia) may control fetal development and differentiation. A crucial mediator of the adaptive response of cells to hypoxia is the transcription factor Hif-1α. In this study, we provide evidence that mesenchymal condensations that give origin to endo...

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Bibliographic Details
Main Authors: Provot, Sylvain, Zinyk, Dawn, Gunes, Yasemin, Kathri, Richa, Le, Quynh, Kronenberg, Henry M., Johnson, Randall S., Longaker, Michael T., Giaccia, Amato J., Schipani, Ernestina
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064828/
https://ncbi.nlm.nih.gov/pubmed/17470636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612023
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