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Thermodynamic and kinetic stability of intermolecular triple helices containing different proportions of C(+)·GC and T·AT triplets

We have used oligonucleotides containing appropriately placed fluorophores and quenchers to measure the stability of 15mer intermolecular triplexes with third strands consisting of repeats of TTT, TTC, TCC and TCTC. In the presence of 200 mM sodium (pH 5.0) triplexes that contain only T·AT triplets...

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Detalles Bibliográficos
Main Authors: James, Peter L., Brown, Tom, Fox, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC206477/
https://ncbi.nlm.nih.gov/pubmed/14500823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg782
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