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Splicing- and cleavage-independent requirement of RNA polymerase II CTD for mRNA release from the transcription site

Eukaryotic cells have a surveillance mechanism that identifies aberrantly processed pre-mRNAs and prevents their flow to the cytoplasm by tethering them near the site of transcription. Here we provide evidence that mRNA release from the transcription site requires the heptad repeat structure of the...

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Détails bibliographiques
Auteurs principaux: Custódio, Noélia, Vivo, Maria, Antoniou, Michael, Carmo-Fonseca, Maria
Format: Artigo
Langue:Inglês
Publié: The Rockefeller University Press 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064756/
https://ncbi.nlm.nih.gov/pubmed/17938247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200612109
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