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DNA-dependent protein kinase in nonhomologous end joining: a lock with multiple keys?

The DNA-dependent protein kinase (DNA-PK) is one of the central enzymes involved in DNA double-strand break (DSB) repair. It facilitates proper alignment of the two ends of the broken DNA molecule and coordinates access of other factors to the repair complex. We discuss the latest findings on DNA-PK...

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Bibliografske podrobnosti
Main Authors: Weterings, Eric, Chen, David J.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2007
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064754/
https://ncbi.nlm.nih.gov/pubmed/17938249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705106
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