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Stress-dependent relocalization of translationally primed mRNPs to cytoplasmic granules that are kinetically and spatially distinct from P-bodies

Cytoplasmic RNA granules serve key functions in the control of messenger RNA (mRNA) fate in eukaryotic cells. For instance, in yeast, severe stress induces mRNA relocalization to sites of degradation or storage called processing bodies (P-bodies). In this study, we show that the translation repressi...

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Bibliographic Details
Main Authors: Hoyle, Nathaniel P., Castelli, Lydia M., Campbell, Susan G., Holmes, Leah E.A., Ashe, Mark P.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2007
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064737/
https://ncbi.nlm.nih.gov/pubmed/17908917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200707010
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