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SMK-1/PPH-4.1–mediated silencing of the CHK-1 response to DNA damage in early C. elegans embryos

During early embryogenesis in Caenorhabditis elegans, the ATL-1–CHK-1 (ataxia telangiectasia mutated and Rad3 related–Chk1) checkpoint controls the timing of cell division in the future germ line, or P lineage, of the animal. Activation of the CHK-1 pathway by its canonical stimulus DNA damage is ac...

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Detalhes bibliográficos
Main Authors: Kim, Seung-Hwan, Holway, Antonia H., Wolff, Suzanne, Dillin, Andrew, Michael, W. Matthew
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064732/
https://ncbi.nlm.nih.gov/pubmed/17908915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705182
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