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Neurotrophin 3 induces structural and functional modification of synapses through distinct molecular mechanisms

The mechanisms by which neurotrophins elicit long-term structural and functional changes of synapses are not known. We report the mechanistic separation of functional and structural synaptic regulation by neurotrophin 3 (NT-3), using the neuromuscular synapse as a model. Inhibition of cAMP response...

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Detalhes bibliográficos
Main Authors: Je, Hyun-Soo, Yang, Feng, Zhou, Jiangzheng, Lu, Bai
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064711/
https://ncbi.nlm.nih.gov/pubmed/17178914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200603061
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