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Rhamm(−/−) fibroblasts are defective in CD44-mediated ERK1,2 motogenic signaling, leading to defective skin wound repair

Rhamm (receptor for hyaluronan-mediated motility) is an hyaluronan binding protein with limited expression in normal tissues and high expression in advanced cancers. To understand its physiological functions and identify the molecular mechanisms underlying these functions, we created mice with a gen...

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Autores principales: Tolg, Cornelia, Hamilton, Sara R., Nakrieko, Kerry-Ann, Kooshesh, Fatemeh, Walton, Paul, McCarthy, James B., Bissell, Mina J., Turley, Eva A.
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064710/
https://ncbi.nlm.nih.gov/pubmed/17158951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200511027
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