Neurofascin assembles a specialized extracellular matrix at the axon initial segment

Action potential initiation and propagation requires clustered Na(+) (voltage-gated Na(+) [Nav]) channels at axon initial segments (AIS) and nodes of Ranvier. In addition to ion channels, these domains are characterized by cell adhesion molecules (CAMs; neurofascin-186 [NF-186] and neuron glia–relat...

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Main Authors: Hedstrom, Kristian L., Xu, Xiaorong, Ogawa, Yasuhiro, Frischknecht, Renato, Seidenbecher, Constanze I., Shrager, Peter, Rasband, Matthew N.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Rockefeller University Press 2007
Ábhair:
Research Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064550/
https://ncbi.nlm.nih.gov/pubmed/17709431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200705119
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