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Global mapping of nucleic acid conformational space: dinucleoside monophosphate conformations and transition pathways among conformational classes

A global conformational space of 6253 dinucleoside monophosphate (DMP) units consisting of RNA and DNA (free and protein/drug-bound) was ‘mapped’ using high resolution crystal structures cataloged in the Nucleic Acid Database (NDB). The torsion angles of each DMP were clustered in a reduced three-di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sims, Gregory E., Kim, Sung-Hou
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2003
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC206451/
https://ncbi.nlm.nih.gov/pubmed/14500824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg750
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