BMP1 controls TGFβ1 activation via cleavage of latent TGFβ-binding protein

Transforming growth factor β1 (TGFβ1), an important regulator of cell behavior, is secreted as a large latent complex (LLC) in which it is bound to its cleaved prodomain (latency-associated peptide [LAP]) and, via LAP, to latent TGFβ-binding proteins (LTBPs). The latter target LLCs to the extracellu...

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Detaylı Bibliyografya
Asıl Yazarlar: Ge, Gaoxiang, Greenspan, Daniel S.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: The Rockefeller University Press 2006
Konular:
Research Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064503/
https://ncbi.nlm.nih.gov/pubmed/17015622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606058
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