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Characterization of AP lyase activities of Saccharomyces cerevisiae Ntg1p and Ntg2p: implications for biological function

Saccharomyces cerevisiae possesses two Escherichia coli endonuclease III homologs, NTG1 and NTG2, whose gene products function in the base excision repair pathway and initiate removal of a variety of oxidized pyrimidines from DNA. Although the glycosylase activity of these proteins has been well stu...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Meadows, Kellen L., Song, Binwei, Doetsch, Paul W.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2003
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206450/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14500818/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg749
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