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Type Iγ phosphatidylinositol phosphate kinase is required for EGF-stimulated directional cell migration

Phosphatidylinositol 4,5-bisphosphate (PI4,5P(2)) modulates a plethora of cytoskeletal interactions that control the dynamics of actin assembly and, ultimately, cell migration. We show that the type Iγ phosphatidylinositol phosphate kinase 661 (PIPKIγ661), an enzyme that generates PI4,5P(2), is requ...

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Detalhes bibliográficos
Main Authors: Sun, Yue, Ling, Kun, Wagoner, Matthew P., Anderson, Richard A.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064448/
https://ncbi.nlm.nih.gov/pubmed/17635937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701078
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