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BUB1 mediation of caspase-independent mitotic death determines cell fate

The spindle checkpoint that monitors kinetochore–microtubule attachment has been implicated in tumorigenesis; however, the relation between the spindle checkpoint and cell death remains obscure. In BUB1-deficient (but not MAD2-deficient) cells, conditions that activate the spindle checkpoint (i.e.,...

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Bibliografiset tiedot
Päätekijät: Niikura, Yohei, Dixit, Amruta, Scott, Ray, Perkins, Guy, Kitagawa, Katsumi
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064447/
https://ncbi.nlm.nih.gov/pubmed/17620410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200702134
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