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Locally controlled inhibitory mechanisms are involved in eukaryotic GPCR-mediated chemosensing

Gprotein–coupled receptor (GPCR) signaling mediates a balance of excitatory and inhibitory activities that regulate Dictyostelium chemosensing to cAMP. The molecular nature and kinetics of these inhibitors are unknown. We report that transient cAMP stimulations induce PIP(3) responses without a refr...

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Detalhes bibliográficos
Main Authors: Xu, Xuehua, Meier-Schellersheim, Martin, Yan, Jianshe, Jin, Tian
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064430/
https://ncbi.nlm.nih.gov/pubmed/17606871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200611096
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