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Flow-enhanced adhesion regulated by a selectin interdomain hinge
L-selectin requires a threshold shear to enable leukocytes to tether to and roll on vascular surfaces. Transport mechanisms govern flow-enhanced tethering, whereas force governs flow-enhanced rolling by prolonging the lifetimes of L-selectin–ligand complexes (catch bonds). Using selectin crystal str...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064400/ https://ncbi.nlm.nih.gov/pubmed/17000883 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606056 |
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