Flow-enhanced adhesion regulated by a selectin interdomain hinge

L-selectin requires a threshold shear to enable leukocytes to tether to and roll on vascular surfaces. Transport mechanisms govern flow-enhanced tethering, whereas force governs flow-enhanced rolling by prolonging the lifetimes of L-selectin–ligand complexes (catch bonds). Using selectin crystal str...

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Detalhes bibliográficos
Main Authors: Lou, Jizhong, Yago, Tadayuki, Klopocki, Arkadiusz G., Mehta, Padmaja, Chen, Wei, Zarnitsyna, Veronika I., Bovin, Nicolai V., Zhu, Cheng, McEver, Rodger P.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2006
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064400/
https://ncbi.nlm.nih.gov/pubmed/17000883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606056
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