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Paraxial protocadherin mediates cell sorting and tissue morphogenesis by regulating C-cadherin adhesion activity

Little is known about how protocadherins function in cell adhesion and tissue development. Paraxial protocadherin (PAPC) controls cell sorting and morphogenetic movements in the Xenopus laevis embryo. We find that PAPC mediates these functions by down-regulating the adhesion activity of C-cadherin....

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Autori principali: Chen, Xuejun, Gumbiner, Barry M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Rockefeller University Press 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064189/
https://ncbi.nlm.nih.gov/pubmed/16847104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200602062
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