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BDNF mobilizes synaptic vesicles and enhances synapse formation by disrupting cadherin–β-catenin interactions

Neurons of the vertebrate central nervous system have the capacity to modify synapse number, morphology, and efficacy in response to activity. Some of these functions can be attributed to activity-induced synthesis and secretion of the neurotrophin brain-derived neurotrophic factor (BDNF); however,...

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Bibliographic Details
Main Authors: Bamji, Shernaz X., Rico, Beatriz, Kimes, Nikole, Reichardt, Louis F.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2006
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064188/
https://ncbi.nlm.nih.gov/pubmed/16831887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200601087
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