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Identification of a novel functional specificity signal within the GPI anchor signal sequence of carcinoembryonic antigen

Exchanging the glycophosphatidylinositol (GPI) anchor signal sequence of neural cell adhesion molecule (NCAM) for the signal sequence of carcinoembryonic antigen (CEA) generates a mature protein with NCAM external domains but CEA-like tumorigenic activity. We hypothesized that this resulted from the...

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Autors principals: Nicholson, Thomas B., Stanners, Clifford P.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064130/
https://ncbi.nlm.nih.gov/pubmed/17438079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200701158
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