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Compartmentalization of androgen receptor protein–protein interactions in living cells

Steroid receptors regulate gene expression in a ligand-dependent manner by binding specific DNA sequences. Ligand binding also changes the conformation of the ligand binding domain (LBD), allowing interaction with coregulators via LxxLL motifs. Androgen receptors (ARs) preferentially interact with c...

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Detalhes bibliográficos
Main Authors: van Royen, Martin E., Cunha, Sónia M., Brink, Maartje C., Mattern, Karin A., Nigg, Alex L., Dubbink, Hendrikus J., Verschure, Pernette J., Trapman, Jan, Houtsmuller, Adriaan B.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2064112/
https://ncbi.nlm.nih.gov/pubmed/17420290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200609178
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