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Identification of prothymosin-α1, the necrosis–apoptosis switch molecule in cortical neuronal cultures
We initially identified a nuclear protein, prothymosin-α1 (ProTα), as a key protein inhibiting necrosis by subjecting conditioned media from serum-free cultures of cortical neurons to a few chromatography steps. ProTα inhibited necrosis of cultured neurons by preventing rapid loss of cellular adenos...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2007
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2064059/ https://ncbi.nlm.nih.gov/pubmed/17353361 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200608022 |
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