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Puf3p, a Pumilio family RNA binding protein, localizes to mitochondria and regulates mitochondrial biogenesis and motility in budding yeast

Puf3p binds preferentially to messenger RNAs (mRNAs) for nuclear-encoded mitochondrial proteins. We find that Puf3p localizes to the cytosolic face of the mitochondrial outer membrane. Overexpression of PUF3 results in reduced mitochondrial respiratory activity and reduced levels of Pet123p, a prote...

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Bibliografiska uppgifter
Huvudupphovsmän: García-Rodríguez, Luis J., Gay, Anna Card, Pon, Liza A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: The Rockefeller University Press 2007
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063939/
https://ncbi.nlm.nih.gov/pubmed/17210948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200606054
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