Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells

Mammalian H/ACA RNPs are essential for ribosome biogenesis, premessenger RNA splicing, and telomere maintenance. These RNPs consist of four core proteins and one RNA, but it is not known how they assemble. By interrogating the site of H/ACA RNA transcription, we dissected their biogenesis in single...

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Autores principales: Darzacq, Xavier, Kittur, Nupur, Roy, Sujayita, Shav-Tal, Yaron, Singer, Robert H., Meier, U. Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: The Rockefeller University Press 2006
Materias:
Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063812/
https://ncbi.nlm.nih.gov/pubmed/16618814
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200601105
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