Kinesin 5–independent poleward flux of kinetochore microtubules in PtK1 cells

Forces in the spindle that align and segregate chromosomes produce a steady poleward flux of kinetochore microtubules (MTs [kMTs]) in higher eukaryotes. In several nonmammalian systems, flux is driven by the tetrameric kinesin Eg5 (kinesin 5), which slides antiparallel MTs toward their minus ends. H...

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Autors principals: Cameron, Lisa A., Yang, Ge, Cimini, Daniela, Canman, Julie C., Kisurina-Evgenieva, Olga, Khodjakov, Alexey, Danuser, Gaudenz, Salmon, E.D.
Format: Artigo
Idioma:Inglês
Publicat: The Rockefeller University Press 2006
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063808/
https://ncbi.nlm.nih.gov/pubmed/16636143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200601075
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