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Skeletons in the p53 tumor suppressor closet: genetic evidence that p53 blocks bone differentiation and development
A series of in vitro tissue culture studies indicated that the p53 tumor suppressor promotes cellular differentiation, which could explain its role in preventing cancer. Quite surprisingly, however, two new in vivo studies (Lengner et al., 2006; Wang et al., 2006) provide genetic evidence that p53 b...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063722/ https://ncbi.nlm.nih.gov/pubmed/16533941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200601114 |
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