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Early aging–associated phenotypes in Bub3/Rae1 haploinsufficient mice

Aging is a highly complex biological process that is believed to involve multiple mechanisms. Mice that have small amounts of the mitotic checkpoint protein BubR1 age much faster than normal mice, but whether other mitotic checkpoint genes function to prevent the early onset of aging is unknown. In...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Baker, Darren J., Jeganathan, Karthik B., Malureanu, Liviu, Perez-Terzic, Carmen, Terzic, Andre, van Deursen, Jan M.A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2006
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063673/
https://ncbi.nlm.nih.gov/pubmed/16476774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200507081
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