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Two binding partners cooperate to activate the molecular motor Kinesin-1

The regulation of molecular motors is an important cellular problem, as motility in the absence of cargo results in futile adenosine triphosphate hydrolysis. When not transporting cargo, the microtubule (MT)-based motor Kinesin-1 is kept inactive as a result of a folded conformation that allows auto...

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Detalhes bibliográficos
Main Authors: Blasius, T. Lynne, Cai, Dawen, Jih, Gloria T., Toret, Christopher P., Verhey, Kristen J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063617/
https://ncbi.nlm.nih.gov/pubmed/17200414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200605099
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