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Loss of stem cell regenerative capacity within aged niches

This work uncovers novel mechanisms of aging within stem cell niches that are evolutionarily conserved between mice and humans and affect both embryonic and adult stem cells. Specifically, we have examined the effects of aged muscle and systemic niches on key molecular identifiers of regenerative po...

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Detalhes bibliográficos
Main Authors: Carlson, Morgan E, Conboy, Irina M
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063610/
https://ncbi.nlm.nih.gov/pubmed/17381551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2007.00286.x
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