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Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes

Protein interacting with c kinase 1 (PICK1) regulates the trafficking of receptors and ion-channels such as AMPA receptors. Traditionally, the PICK1 PDZ domain is regarded as an adaptor capable of binding to receptors trafficked by PICK1, and the lipid-binding BAR domain functions to tether PICK1 di...

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Autori principali: Pan, Lifeng, Wu, Hao, Shen, Chong, Shi, Yawei, Jin, Wenying, Xia, Jun, Zhang, Mingjie
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2007
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063473/
https://ncbi.nlm.nih.gov/pubmed/17914463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601860
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