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Clustering and synaptic targeting of PICK1 requires direct interaction between the PDZ domain and lipid membranes
Protein interacting with c kinase 1 (PICK1) regulates the trafficking of receptors and ion-channels such as AMPA receptors. Traditionally, the PICK1 PDZ domain is regarded as an adaptor capable of binding to receptors trafficked by PICK1, and the lipid-binding BAR domain functions to tether PICK1 di...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2063473/ https://ncbi.nlm.nih.gov/pubmed/17914463 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601860 |
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