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Telomerase activity in normal and malignant mammalian tissues: feasibility of telomerase as a target for cancer chemotherapy.

Telomerase, a ribonucleoprotein enzyme, has been found in immortalized but not in most somatic adult human tissues, and thus emerged as a novel target for cancer chemotherapy. However, its usefulness could still be limited by normal tissue toxicity. This study compares enzyme activity in tissues and...

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Detalhes bibliográficos
Main Authors: Burger, A. M., Bibby, M. C., Double, J. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group|1 1997
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063310/
https://ncbi.nlm.nih.gov/pubmed/9052403
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