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Role of glucose-6-phosphate dehydrogenase inhibition in the antiproliferative effects of dehydroepiandrosterone on human breast cancer cells.

Epidemiological and experimental studies suggest that dehydroepiandrosterone (DHEA) exerts a protective effect against breast cancer. It has been proposed that the non-competitive inhibition of glucose-6-phosphate dehydrogenase (G6PD) contributes to DHEA antitumor action. We evaluated the effects of...

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Autors principals: Di Monaco, M., Pizzini, A., Gatto, V., Leonardi, L., Gallo, M., Brignardello, E., Boccuzzi, G.
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group|1 1997
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063293/
https://ncbi.nlm.nih.gov/pubmed/9052415
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