Enhancement of 5-aminolaevulinic acid-induced photodynamic therapy in normal rat colon using hydroxypyridinone iron-chelating agents.

Currently, the clinical use of 5-aminolaevulinic acid (ALA)-induced protoporphyrin IX (PPIX) for photodynamic therapy (PDT) is limited by the maximum tolerated oral ALA dose (60 mg kg(-1)). This study investigates whether hydroxypyridinone iron-chelating agents can be used to enhance the tissue leve...

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Autori principali: Curnow, A., McIlroy, B. W., Postle-Hacon, M. J., Porter, J. B., MacRobert, A. J., Bown, S. G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group|1 1998
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063198/
https://ncbi.nlm.nih.gov/pubmed/9823966
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