Biochemical basis of 5-aminolaevulinic acid-induced protoporphyrin IX accumulation: a study in patients with (pre)malignant lesions of the oesophagus.

Administration of 5-aminolaevulinic acid (ALA) leads to porphyrin accumulation in malignant and premalignant tissues, and ALA is used as a prodrug in photodynamic therapy (PDT). To understand the mechanism of porphyrin accumulation after the administration of ALA and to investigate whether ALA-induc...

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Bibliographic Details
Main Authors: Hinnen, P., de Rooij, F. W., van Velthuysen, M. L., Edixhoven, A., van Hillegersberg, R., Tilanus, H. W., Wilson, J. H., Siersema, P. D.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group|1 1998
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2063052/
https://ncbi.nlm.nih.gov/pubmed/9744510
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