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Enhanced radiosensitivity in experimental tumours following erythropoietin treatment of chemotherapy-induced anaemia.

The radiosensitivity of solid tumours in anaemic rats treated with recombinant human erythropoietin (rhEPO, epoetin beta) was studied. Anaemia was induced by a single dose of carboplatin (45 mg kg(-1) i.v.), resulting in a reduction in the haemoglobin concentration by 30%. In a second group, the dev...

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Autori principali: Thews, O., Koenig, R., Kelleher, D. K., Kutzner, J., Vaupel, P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group|1 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062974/
https://ncbi.nlm.nih.gov/pubmed/9743294
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