Enhanced expression of the urokinase-type plasminogen activator gene and reduced colony formation in soft agar by ectopic expression of PU.1 in HT1080 human fibrosarcoma cells.

To investigate the cell biological function of PU.1, a member of the Ets family of transcription factors, a vector capable of expressing the protein was transfected into HT1080 human fibrosarcoma cells. Exogenous expression of PU.1 in HT1080 cells reduced colony-forming efficiency but stimulated cel...

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Détails bibliographiques
Auteurs principaux: Kondoh, N., Yamada, T., Kihara-Negishi, F., Yamamoto, M., Oikawa, T.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group|1 1998
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062971/
https://ncbi.nlm.nih.gov/pubmed/9743289
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