Measuring the Binding Stoichiometry of HIV-1 Gag to Very-Low-Density Oligonucleotide Surfaces Using Surface Plasmon Resonance Spectroscopy

The interaction of the HIV Gag polyprotein with nucleic acid is a critical step in the assembly of viral particles. The Gag polyprotein is composed of the matrix (MA), capsid (CA), and nucleocapsid (NC) domains. The NC domain is required for nucleic acid interactions, and the CA domain is required f...

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Bibliographic Details
Main Authors: Stephen, Andrew G., Datta, Siddhartha A.K., Worthy, Karen M., Bindu, Lakshman, Fivash, Matthew J., Turner, Kevin B., Fabris, Daniele, Rein, Alan, Fisher, Robert J.
Format: Artigo
Language:Inglês
Published: The Association of Biomolecular Resource Facilities 2007
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2062552/
https://ncbi.nlm.nih.gov/pubmed/17916799
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