Multiple mutant of Escherichia coli synthesizing virtually thymineless DNA during limited growth.

The dut gene of Escherichia coli encodes deoxyuridine triphosphatase, an enzyme that prevents the incorporation of dUTP into DNA and that is needed in the de novo biosynthesis of thymidylate. We produced a conditionally lethal dut(Ts) mutation and isolated a phenotypic revertant that had a mutation...

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Pubblicato in:	J Bacteriol
Autori principali:	el-Hajj, H H, Wang, L, Weiss, B
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC206231/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1624437/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.13.4450-4456.1992
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