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The VanS-VanR two-component regulatory system controls synthesis of depsipeptide peptidoglycan precursors in Enterococcus faecium BM4147.

Plasmid pIP816 of Enterococcus faecium BM4147 confers inducible resistance to vancomycin and encodes the VanH dehydrogenase and the VanA ligase for synthesis of depsipeptide-containing peptidoglycan precursors which bind the antibiotic with reduced affinity. We have characterized a cluster of five g...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Arthur, M, Molinas, C, Courvalin, P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1556077/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.174.8.2582-2591.1992
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