Disaggregation of Alzheimer β-amyloid by site-directed mAb
In Alzheimer disease, β-amyloid peptide accumulates in the brain as insoluble amyloid plaques. Amyloid filaments, similar to those found in amyloid plaques, can be assembled in vitro from chemically synthesized β-peptides. In this study, we report that antibodies raised against the N-terminal region...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20576/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.4109 |
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