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Differential utilization of CCR5 by macrophage and T cell tropic simian immunodeficiency virus strains

Certain chemokine receptors serve as cofactors for HIV type 1 envelope (env)-mediated cell–cell fusion and virus infection of CD4-positive cells. Macrophage tropic (M-tropic) HIV-1 isolates use CCR5, and T cell tropic (T-tropic) strains use CXCR4. To investigate the cofactors used by simian immunode...

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Published in:Proc Natl Acad Sci U S A
Main Authors: Edinger, Aimee L., Amedee, Angela, Miller, Karen, Doranz, Benjamin J., Endres, Michael, Sharron, Matthew, Samson, Michel, Lu, Zhao-hai, Clements, Janice E., Murphey-Corb, Michael, Peiper, Stephen C., Parmentier, Marc, Broder, Christopher C., Doms, Robert W.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 1997
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20558/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108095/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.4005
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