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Gene cluster controlling conversion to alginate-overproducing phenotype in Pseudomonas aeruginosa: functional analysis in a heterologous host and role in the instability of mucoidy.

Conversion to mucoidy, caused by the overproduction of the exopolysaccharide alginate in laboratory and cystic fibrosis strains of Pseudomonas aeruginosa, can occur via frameshift or nonsense mutations in the second gene of the algU mucA mucB cluster. The first gene of the cluster, algU, encodes a p...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Principais autores: Schurr, M J, Martin, D W, Mudd, M H, Deretic, V
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1994
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205510/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8195094/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.11.3375-3382.1994
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