gyrB mutations in coumermycin A1-resistant Borrelia burgdorferi.

We have isolated and characterized mutants of Borrelia burgdorferi that are resistant to the antibiotic coumermycin A1, which targets the B subunit of DNA gyrase. Mutants had either 100- or 300-fold higher resistance to coumermycin A1 than wild-type B. burgdorferi. In each case, a single point mutat...

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Pubblicato in:	J Bacteriol
Autori principali:	Samuels, D S, Marconi, R T, Huang, W M, Garon, C F
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205466/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8188609/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.10.3072-3075.1994
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