In vitro restoration of T cell responses in tuberculosis and augmentation of monocyte effector function against Mycobacterium tuberculosis by natural inhibitors of transforming growth factor β

We examined the capacity of the naturally occurring inhibitors of transforming growth factor β (TGF-β), decorin and latency associated peptide (LAP), to reverse depressed T cell functions in peripheral blood mononuclear cells (PBMCs) from patients with pulmonary tuberculosis (TB) in vitro and to cou...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hirsch, Christina S., Ellner, Jerrold J., Blinkhorn, Richard, Toossi, Zahra
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1997
Soggetti:	Biological Sciences
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC20544/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9108081/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.8.3926
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