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Biosynthesis of o-succinylbenzoic acid in Bacillus subtilis: identification of menD mutants and evidence against the involvement of the alpha-ketoglutarate dehydrogenase complex.

The biosynthesis of o-succinylbenzoic acid (OSB), the first aromatic intermediate involved in the biosynthesis of menaquinone (vitamin K2) is demonstrated for the first time in the gram-positive bacterium Bacillus subtilis. Cell extracts were found to contain isochorismate synthase, 2-succinyl-6-hyd...

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Bibliographic Details
Published in:J Bacteriol
Main Authors: Palaniappan, C, Taber, H, Meganathan, R
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1994
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205404/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8169214/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.9.2648-2653.1994
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