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Identification of a genetic locus involved in the biosynthesis of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked polysialic acid capsule of serogroup B Neisseria meningitidis.

We characterized the genetic defect of a capsule-deficient serogroup B meningococcal strain created by Tn916 mutagenesis. The transposon insertion interrupts a capsule biosynthesis gene, synX, which is involved in the production of N-acetyl-D-mannosamine, a precursor of the (alpha 2-->8)-linked poly...

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Detalhes bibliográficos
Publicado no:J Bacteriol
Principais autores: Swartley, J S, Stephens, D S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC205225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8113198/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jb.176.5.1530-1534.1994
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